Prognosis

Thrombus accumulation can accept one of 5 outcomes: propagation, embolization, dissolution, alignment and alignment with recanalization.5

Propagation of a array occurs appear the administration of the heart. This agency that it is anterograde in veins or astern in arteries.

Embolization occurs if the array breach chargeless from the vascular bank and becomes mobile. A venous emboli (most acceptable from abysmal venous occlusion in the lower extremities) will biking through the systemic circulation, ability the appropriate ancillary of the heart, and biking through the pulmonary avenue consistent in a pulmonary embolism. On the added hand, arterial occlusion consistent from hypertension or atherosclerosis can become adaptable and the consistent emboli can choke any avenue or arteriole afterwards of the array formation. This agency that bookish stroke, myocardial infarction, or any added agency can be affected.

Dissolution occurs if fibrinolytic mechanisms breach up the array and claret breeze is adequate to the vessel. This may be aided by drugs (for archetype afterwards occlusion of a coronary artery). The best acknowledgment to fibrinolytic drugs is aural a brace of hours, afore the fibrin cobweb of the array has been absolutely developed.

Organization and recanalization involves the ingrowth of bland beef cells, fibroblasts and endothelium into the fibrin-rich thrombus. If recanalization gain it provides capillary-sized channels through the array for chain of claret breeze through the absolute array but may not restore acceptable claret breeze for the metabolic needs of the afterwards tissue.